الموقع الرسمي جامعة تشرين

Introduction: Carcinoma of the colon & rectum usually affects old patients after the fifth or sixth decade of life and is unusual in patients under 40 years of age. Material & Methods : This study describes the clinipathological features of 15 young native Syrian patients ( 40 year & younger ) who were diagnosed as having colorectal carcinoma ( Adenocarcinoma) at Al-Assad University Hospital in Lattakia –Syria, in the period from 1995 –2003. Patients aged ( 17 – 39 ) years. (11 males, 4 females ). Results : The patients were predominantly male, mainly presenting with rectal bleeding intestinal obstruction or abdominal pain. Three patients had ulcerative colitis. One patient had familial polyposis Five tumors were in rectosigmoid, 5 in descending colon, 2 in transverse colon, and 3 in ascending colon. There were three stages B2, 8 stage C1, 4 stage C2 ( according to Astler-Coller modification of Dukes' classification . Summary : We present in this study the clinipathological features of 15 young native Syrian patients ( 40 year & younger ) who were diagnosed as having colorectal carcinoma. The patients presented at later stage (C1, C2 ) in more than 2/3 of cases compared with the control group.